Journal of Genetic Engineering and Biotechnology

Table 2 Correlation between methylated PTEN and SMAD4 with other parameters

From: Alterations of PTEN and SMAD4 methylation in diagnosis of breast cancer: implications of methyl II PCR assay

Factors	PTEN methylation status		SMAD4 methylation status
Factors	R	P value	R	P value
Age	− 0.09	0.315	− 0.017	0.844
Menopause	− 0.1	0.270	− 0.016	0.861
CEA	0.209	0.017	0.086	0.329
CA15-3	0.395	0.0001	0.265	0.002
Tumor stage	0.507	0.0001	0.320	0.004
Tumor grade	0.492	0.0001	0.329	0.003
Lymph node	0.454	0.0001	0.323	0.004
ER	0.203	0.07	0.120	0.289
PgR	0.315	0.004	0.237	0.034
HER2	0.042	0.711	0.194	0.084
Molecular subtypes	0.321	0,0001	0,154	0.175
Methylated SMAD4	0.727	0.0001

*Correlations were determined according to Pearson coefficient; P < 0.05 was significant

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