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Table 5 List of hub genes and value of the degree of connectivity

From: Identification of molecular biomarkers and pathways of NSCLC: insights from a systems biomedicine perspective

Gene symbol

Gene name

Degree of connectivity

ESR1

Estrogen receptor 1

80

AR

Androgen receptor

51

LRRK2

Leucine-rich repeat kinase 2

45

CFTR

CF transmembrane conductance regulator

40

ZBTB16

Zinc finger and BTB domain-containing 16

39

ERBB2

Erb-B2 receptor tyrosine kinase 2

38

EEF1A2

Eukaryotic translation elongation factor 1 alpha 2

36

DSP

Desmoplakin

39

CDK1

Cyclin-dependent kinase 1

36

PHGDH

Phosphoglycerate dehydrogenase

35

SFN

Stratifin

35

SOX2

SRY-box transcription factor 2

35