Table 2 The functional analyses of downregulated genes to identify top 15 GO terms
Category | Term name | Count | P value |
|---|---|---|---|
CC | GO:0070062—extracellular exosome | 170 | 1.57E–14 |
CC | GO:0005615—extracellular space | 97 | 3.11E–12 |
CC | GO:0005886—plasma membrane | 200 | 2.84E–08 |
CC | GO:0005887—integral component of plasma membrane | 86 | 2.00E–07 |
CC | GO:0005576—extracellular region | 93 | 5.62E–07 |
BP | GO:0045429—positive regulation of nitric oxide biosynthetic process | 9 | 1.02E–04 |
BP | GO:0007165—signal transduction | 65 | 1.72E–04 |
BP | GO:0050714—positive regulation of protein secretion | 8 | 2.08E–04 |
BP | GO:0005975—carbohydrate metabolic process | 17 | 3.93E–04 |
BP | GO:0050873—brown fat cell differentiation | 7 | 7.29E–04 |
MF | GO:0005044—scavenger receptor activity | 8 | 0.001241 |
MF | GO:0008083—growth factor activity | 14 | 0.004251 |
MF | GO:0042803—protein homodimerization activity | 40 | 0.005049 |
MF | GO:0005088—Ras guanyl-nucleotide exchange factor activity | 11 | 0.00664 |
MF | GO:0003779—actin binding | 19 | 0.008431 |