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Table 1 The functional analyses of upregulated genes to identify top 15 GO terms

From: Identification of molecular biomarkers and pathways of NSCLC: insights from a systems biomedicine perspective

Category

Term name

Count

P value

BP

GO:0008544—epidermis development

20

2.13E–14

BP

GO:0030216—keratinocyte differentiation

18

5.06E–13

BP

GO:0030855—epithelial cell differentiation

11

2.79E–06

BP

GO:0031424—keratinization

9

8.65E–06

BP

GO:0007067—mitotic nuclear division

19

9.58E–06

CC

GO:0001533—cornified envelope

10

4.31E–07

CC

GO:0030057—desmosome

7

8.46E–06

CC

GO:0000775—chromosome, centromeric region

9

2.51E–05

CC

GO:0005737—cytoplasm

148

3.40E–05

CC

GO:0005882—intermediate filament

11

1.45E–04

MF

GO:0005198—structural molecule activity

24

3.60E–09

MF

GO:0008017—microtubule binding

15

1.60E–04

MF

GO:0001758—retinal dehydrogenase activity

4

3.18E–04

MF

GO:0005200—structural constituent of cytoskeleton

10

5.89E–04

MF

GO:0042803—protein homodimerization activity

30

0.001048

  1. BP biological process, CC cellular component, MF molecular function