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Table 2 Comparison between different studied vitamin D receptors genes genotypes regarding the related investigated parameters

From: Association of some dietary ingredients, vitamin D, estrogen, and obesity polymorphic receptor genes with bone mineral density in a sample of obese Egyptian women

Parameters

N = 97

Non-osteoporotic

N = 45

Osteoporotic

N = 52

Taq1 vit. D receptor

Homozygous

No: 26

Heterozygous

No: 19

P

Homozygous

No: 34

Heterozygous

No: 18

P

Mean ± SD

Mean ± SD

 

Mean ± SD

Mean ± SD

 

Age (years)

38.39 ± 7.11

38.68 ± 9.05

0.907

54.96 ± 5.15

53.41 ± 5.61* #

0.322

Weight (kg)

79.34 ± 20.21

78.64 ± 22.35

0.885

81.52 ± 12.80

72.75 ± 21.37

0.135

Height (cm)

157.69 ± 4.42

155.95 ± 6.95

0.229

155.62 ± 4.77

152.00 ± 9.09* #

0.156

BMI kg/m2)

31.89 ± 7.91

31.96 ± 9.93

0.978

33.78 ± 5.85

31.77 ± 1.07

0.386

Vit D intake( ųg)

7.22 ± 1.80

6.59 ± 2.71

0.622

5.81 ± 2.04

6.88 ± .3.24

0.976

Serum vit. D (ng/mL)

25.53 ± 8.60

23.11 ± 6.56

0.389

23.18 ± 9.25

25.44 ± 6.45

0.410

Calcium intake( mg)

689.13 ± 25.80

613.54 ± 27.24

0.164

604.17 ± 28.58.

601.70 ± 29.65* #

0.515

Serum calcium (mg/dL)

9.92 ± 0.81

9.28 ± 0.67

0.081

9.26 ± .0.77

9.19 ± .0.59

0.014*

Apa1 vit. D receptor

Homozygous

No: 36

Heterozygous

No: 9

P

Homozygous

No: 33

Heterozygous

No: 18

P

Mean ± SD

Mean ± SD

 

Mean ± SD

Mean ± SD

 

Age (years)

38.39 ± 7.76

39.24 ± 9.24

0.317

55.03 ± 4.48

53.48 ± 6.62

0.383

Weight (kg)

75.35 ± 2.04

93.81 ± 3.29

0.036*

80.48 ± 1.61

73.86 ± 1.70

0.131

Height (cm)

156.57 ± 5.26

156.96 ± 5.62

0.245

153.94 ± 6.75

154.89 ± 6.94* #

0.814

BMI Kg/m2)

30.67 ± 7.94

31.92 ± 8.71

0.056

34.28 ± 8.44

30.62 ± 6.28

0.107

Vit D intake( ųg)

6.20 ± 1.47

5.91 ± 2.33

0.632

6.16 ± 2.48

6.13 ± 1.72

0.621

Serum vit. D (ng/mL)

24.80 ± 8.16

24.54 ± 7.84

0.513

25.78 ± 9.83

21.11 ± 3.62

0.077

Calcium intake( mg)

686.53 ± 25.19

618.77 ± 27.63

0.474

609.19 ± 24.35

607.49 ± 29.31

0.172

Serum calcium (mg/dL

9.61 ± 0. .60

9.32 ± 0.62

0.332

9.14 ± 0.52

9.08 ± 0.59

0.010*

  1. BMI body mass index, vit. D Vitamin D
  2. *P < 0.05 homozygous vs. heterozygous
  3. #P < 0.05 non-osteoporotic vs. osteoporotic