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Fig. 1 | Journal of Genetic Engineering and Biotechnology

Fig. 1

From: Encapsulated VEGF121-PLA microparticles promote angiogenesis in human endometrium stromal cells

Fig. 1

Diagrammatic representation of endometrium regeneration using PLA-VEGF: (1) A woman who is not able to conceive with thin endometrium condition. (2) Collection of the endometrium stromal cells (hESC) from the patient’s endometrium tissues via. hysterectomy. (3) Production of recombinant VEGF121. (4) Encapsulation of rVEGF121 with poly-l-lactide. (5) Injection of the PLA-VEGF121 into the thin endometrium (uterine lining) with the help of IUI catheter. (6) After successful regeneration of the endometrium, embryo which was prepared; transferred in the uterine. (7) After the successful transfer of the healthy embryo, the woman gets pregnant. Successful implantation lies in a fertile environment (i.e., endometrium). In regenerating the endometrium, there are high chances of successful implantation and pregnancy

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