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Fig. 6 | Journal of Genetic Engineering and Biotechnology

Fig. 6

From: Biogenic synthesis of gold nanoparticles using Argemone mexicana L. and their cytotoxic and genotoxic effects on human colon cancer cell line (HCT-15)

Fig. 6

a Representative histogram showing caspase-3 activity in HCT-15 cells. Error bars indicate the standard deviation of three independent experiments (n = 3). Levels of significance in caspase-3 activity, μmolpNA/min/ml between control and AM-AuNPs exposed cell samples assessed by Student’s t test are marked by ***p < 0.0001, which was found to be increased significantly in protein samples obtained from 24 h and 48 h post exposure periods as compared to control cell samples. b Histogram showing analysis of Annexin V-FITC-PI staining of AM-AuNP-treated HCT-15 cells for 0, 24, and 48 h. Data presented were expressed as mean ± SD. Significant differences are indicated **p < 0.001 found to be increased significantly in cell samples obtained from 24 and 48 h post exposure to AM-AuNPs as compared to normal control cells

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