TY - JOUR AU - Desriani AU - Azamris AU - Ghaissani, Shabrina S. AU - Kinanti, Senja R. AU - Warisman, Muhammad A. AU - Fitria, N. PY - 2021 DA - 2021/01/11 TI - Design and characterization of a SYBR Green I-based melting curve method for investigation of HER2I655V polymorphism in breast cancer JO - Journal of Genetic Engineering and Biotechnology SP - 6 VL - 19 IS - 1 AB - Breast cancer is a disease in which cell grows rapidly forming a mass in the breast. HER2 polymorphisms Ile655Val have been studied as biomarkers for breast cancer and may comprise a risk factor of cardiac toxicity for breast cancer-consuming trastuzumab. Aim of work: In this study, we developed a simple, low cost, and rapid test to detect polymorphism at HER2 gene using SYBR Green I-based melting curve method. SN - 2090-5920 UR - https://doi.org/10.1186/s43141-020-00108-9 DO - 10.1186/s43141-020-00108-9 ID - Desriani2021 ER -