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Table 4 Association between rs12331678 and clinicopathological features

From: Heparanase (HPSE) gene polymorphism (rs12503843) contributes as a risk factor for hepatocellular carcinoma (HCC): a pilot study among Egyptian patients

Variables

rs12331678

P

AA (n = 1)

CA (n = 22)

CC (n = 47)

No.

%

No.

%

No.

%

ALT

 Mean ± SD

65.0

48.05 ± 23.08

48.51 ± 38.12

0.652

AST

 Mean ± SD

25.0

53.91 ± 24.62

62.32 ± 37.42

0.293

AFP

 Mean ± SD

949.0

1357.46 ± 2958.08

1090.62 ± 2517.93

0.695

Child-Pugh score

 A

0

0.0

12

54.5

30

63.8

0.345

 B

1

100.0

10

45.5

15

31.9

 C

0

0.0

0

0.0

2

4.3

Number of hepatic focal lesion

 1

1

100.0

13

59.1

32

68.1

MCP = 0.526

 2

0

0.0

4

18.2

10

21.3

 3

0

0.0

3

13.6

1

2.1

 > 3

0

0.0

2

9.1

4

8.5

Size (cm)

 Mean ± SD

5.0

5.43 ± 3.47

4.91 ± 3.03

0.796

HCV

 Negative

1

100.0

2

9.1

4

8.5

MCP = 0.129

 Positive

0

0.0

20

90.9

43

91.5

  1. MC Monte Carlo