Journal of Genetic Engineering and Biotechnology

Table 2 Genotypic and allelic frequencies of HPSE SNP in HCC and control group

From: Heparanase (HPSE) gene polymorphism (rs12503843) contributes as a risk factor for hepatocellular carcinoma (HCC): a pilot study among Egyptian patients

SNP	Patients (n = 70)	Control (n = 30)	OR	95% CI	χ²	P
SNP	%	%	OR	95% CI	χ²	P
rs12331678
AA	1.4	0.0	-	-	1.674	0.553
CA	31.4	43.3	0.599	0.25–1.44
CC	67.1	56.7	1.563	0.65–3.76
Allele
A	17.1	21.7	0.748	0.35–1.59	0.570	0.450
C	82.9	78.3	1.337	0.63–2.84	0.570	0.450
rs12503843
TT	5.7	0.0	–	–
CT	41.4	26.7	1.945	0.76–4.97	3.858	0.128
CC	52.9	73.3	0.408	0.16–1.04
Allele
T	26.4	13.3	2.335	1.01–5.37
C	73.6	86.7	0.428	0.19–0.98	4.130*	0.042*

χ² chi-square test
*Statistically significant at P ≤ 0.05

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