Skip to main content

Table 1 Selected clinical and demographic characteristics of patients and controls

From: Heparanase (HPSE) gene polymorphism (rs12503843) contributes as a risk factor for hepatocellular carcinoma (HCC): a pilot study among Egyptian patients

Variables

Patients (n = 70)

Mean ± SD

Control (n = 30)

Mean ± SD

Test of sig.

P

Demographic data

 Age, years

60.40 ± 10.47

60.64 ± 7.81

χ2 = 0.233

0.898

 Sex, n (%)

M, 65(92.9%); F, 5(7.1%)

M, 27 (90%); F, 3 (10%)

t = 0.128

0.694

 HCV carriers, n (%)

43 (61%)

0 (0%)

  

Hematological profile

 HB

12.53 ± 1.61

13.36 ± 13.36

t = 2.531

< 0.001*

 RBCs.

4.35 ± 0.63

4.65 ± 0.39

t = 2.821*

< 0.001*

 TLC

5.23 ± 1.88

6.61 ± 1.44

t = 3.605

< 0.001*

 PLT

122.53 ± 60.47

270.27 ± 71.36

U = 134.500

< 0.001*

 Pro. Conc.

71.97 ± 14.92

95.47 ± 5.04

t = 11.711*

< 0.001*

 INR

1.28 ± 0.20

1.02 ± 0.04

t = 11.711*

< 0.001*

Biochemical parameters

 Creatinine

0.91 ± 0.23

1.0 ± 0.15

U = 723.50*

0.13

 AST

59.14 ± 33.92

32.30 ± 5.93

U = 343.0*

< 0.001*

 ALT

48.60 ± 33.69

25.77 ± 6.73

U = 407.50*

< 0.001*

 Total bilirubin

1.34 ± 0.68

1.08 ± 0.13

U = 944.50*

0.426

 Direct bilirubin

0.57 ± 0.43

0.18 ± 0.08

U = 332.0*

< 0.001*

 Albumin

3.31 ± 0.62

4.31 ± 0.61

t = 7.375*

< 0.001*

 AFP

1172.46 ± 2627.92

6.04 ± 1.05

U = 199.50*

< 0.001*

Child-Pugh score

 A

60.0%

   

 B

37.1%

   

 C

2.9%

   

Focal lesion

 Size (cm)

5.08 ± 3.14

   

 Number

  1

65.7%

   

  2

20.0%

   

  3

5.7%

   

  > 3

8.6%

   
  1. t Student’s t test, U Mann-Whitney test
  2. *Statistically significant at P ≤ 0.05