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Table 5 Anticancer activity of biological metal nanoparticles

From: Biogenic nanoparticles: a comprehensive perspective in synthesis, characterization, application and its challenges

Biological agent used for synthesis

Nanoparticle

Cell line

IC50 value

Reference

Marsilea quadrifolia

Silver

Human ovarian teratocarcinoma (PA-1) and lung adenocarcinoma (A549)

45.88 μg/mL and 52.015 μg/mL

[25]

Morinda pubescens

Silver

HEP G2 (Human Epithelium cells of liver cancer

937 μg/mL

[129]

Nepeta deflersiana

Silver

Human cervical cancer cells (HeLa)

5 μg/mL

[130]

Murraya koenigii

Silver

HT-29 colon cancer

26.05 μg/mL

[131]

Cyanobacterium Nostoc sp. strain HKAR-2.

Silver

MCF-7 cells

27.5 μg/mL.

[132]

Piper nigrum

Silver

MCF-7 and Hep-2 cells

52 mL, 54 μg/mL

[133]

Ficus religiosa

Silver

A549 and Hep2 cells

1.9 μg/mL and 1.6 μg/mL

[134]

Solanum xanthocarpum

Gold

HCT 15 human colon cancer

–

[135]

Streptomyces sp.

Gold

HeLa

350 μg/mL

[136]

Evolvulus alsinoides

Palladium

Human ovarian cancer A2780 cells

–

[137]

Gloriosa superb

Platinum and palladium

MCF-7 (human breast adenocarcinoma

49.65 ± 1.99% and 36.26 ± 0.91%

[138]

Barleria prionitis

Platinum

Paladium

Human breast adenocarcinoma (MCF-7)

–

[139]

Sargassum muticum

Iron oxide nanoparticles

HeLa cells, MCF-7 cells, HepG2 cells, and human cell lines for leukemia Jurkat

1.1 μg/mL (HepG2), 18.75 ± 2.1 μg/mL (MCF-7), 12.5 ± 1.7 μg/mL (HeLa), and 6.4 ± 2.3 μg/mL (Jurkat)

[140]

Albizia lebbeck

Zinc oxide

MDA-MB 231 and MCF-7

48.5, 48.7, and 60.2 μg/mL

[107]

Costus pictus D. Don medicinal

Zinc oxide

DLA

–

[63]

black bean extract

Copper oxide

HeLa

–

[115]

Ficus religiosa

Copper oxide

A549 cells

200 μg/mL

[127]