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Journal of Genetic Engineering and Biotechnology

Table 5 Y randomization test

From: In silico design and molecular docking study of CDK2 inhibitors with potent cytotoxic activity against HCT116 colorectal cancer cell line

Model

R

R2

Q2

Original

0.860062

0.739706

0.554712

 Random 1

0.569068

0.323839

−1.17969

 Random 2

0.556022

0.309161

−0.34937

 Random 3

0.427541

0.182791

−0.53108

 Random 4

0.501596

0.251598

−0.85524

 Random 5

0.645348

0.416475

0.063014

 Random 6

0.502871

0.252879

−0.52581

 Random 7

0.522143

0.272633

−0.24368

 Random 8

0.595235

0.354305

−1.92796

 Random 9

0.423402

0.179269

−0.35291

 Random 10

0.588755

0.346633

−0.06237

Random models parameters

  

 Average R

0.533198

  

 Average R2

0.288958

  

 Average Q2

−0.59651

  

 cRp2

0.580402

  
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