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Table 4 Statistical parameters of descriptor

From: In silico design and molecular docking study of CDK2 inhibitors with potent cytotoxic activity against HCT116 colorectal cancer cell line

Descriptor

Coefficient

ME

VIF

t stat

p value

SE

nS

−0.1249

0.053941

1.174334

−1.49834

0.150477

0.0833

GATS5s

−5.1376

2.446025

3.119743

−4.64905

0.000175

1.1051

VR1_Dze

0.0003

−0.0787

1.12511

3.097051

0.005934

0.0001

ETA_dBetaP

12.7903

−1.50015

2.717113

5.457748

2.89E-05

2.3435

L3i

−0.1736

0.078893

1.517541

−1.72007

0.101668

0.1009

  1. Key: ME mean effect, VIF variance inflation factor, SE standard error