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Table 2 The primary protein sequence analysis of eight Mur family proteins from A. baumannii

From: Prioritization of Mur family drug targets against A. baumannii and identification of their homologous proteins through molecular phylogeny, primary sequence, and structural analysis

Gene Name Accession No. Protein sequence analysis
AA Mw (KDa) pI GRAVY II AI D EC HL (h) L + R − R
MurA B0V7N7 418 44.6 5.12 0.117 26.61 104.55 1 17545 >10 Cyto (Arg + Lys) 39 (Asp + Glu) 55
MurB B0V744 353 39.7 6.18 − 0.161 31.19 99.94 2 39880 >10 Cyto (Arg + Lys) 30 (Asp + Glu) 35
MurC B0V9F6 482 52.8 5.64 − 0.172 31.16 98.32 3 18005 >10 Cyto (Arg + Lys) 49 (Asp + Glu 62
MurD B0VDD5 455 48.6 6.14 0.042 35.90 105.47 3 19285 >10 Cyto (Arg + Lys) 43 (Asp + Glu) 48
MurE A0A0R4J6I7 499 54.9 5.48 − 0.225 32.23 90.78 3 47120 >10 Cyto (Arg + Lys) 41 (Asp + Glu) 58
MurF A0A0R4J6Z4 466 50.8 5.87 − 0.130 33.75 93.45 3 25565 >10 Cyto (Arg + Lys) 37 (Asp + Glu) 49
MraY B0V8P2 372 40.9 9.54 0.781 25.10 126.32 1 70360 >10 CIM (Arg + Lys) 26 (Asp + Glu) 17
MurG B0V9F5 365 39.4 9.02 0.051 39.12 97.34 2 20190 >10 Cyto (Arg + Lys) 34 (Asp + Glu) 28
  1. AA amino acid, Mw molecular weight, pI isoelectric point, GRAVY grand average of hydropathicity, II instability index, AI aliphatic index, D domain, EC extinction coefficients, L location, + R positively charged residues, − R negatively charged residues