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Table 2 The primary protein sequence analysis of eight Mur family proteins from A. baumannii

From: Prioritization of Mur family drug targets against A. baumannii and identification of their homologous proteins through molecular phylogeny, primary sequence, and structural analysis

Gene Name

Accession No.

Protein sequence analysis

AA

Mw (KDa)

pI

GRAVY

II

AI

D

EC

HL (h)

L

+ R

− R

MurA

B0V7N7

418

44.6

5.12

0.117

26.61

104.55

1

17545

>10

Cyto

(Arg + Lys) 39

(Asp + Glu) 55

MurB

B0V744

353

39.7

6.18

− 0.161

31.19

99.94

2

39880

>10

Cyto

(Arg + Lys) 30

(Asp + Glu) 35

MurC

B0V9F6

482

52.8

5.64

− 0.172

31.16

98.32

3

18005

>10

Cyto

(Arg + Lys) 49

(Asp + Glu 62

MurD

B0VDD5

455

48.6

6.14

0.042

35.90

105.47

3

19285

>10

Cyto

(Arg + Lys) 43

(Asp + Glu) 48

MurE

A0A0R4J6I7

499

54.9

5.48

− 0.225

32.23

90.78

3

47120

>10

Cyto

(Arg + Lys) 41

(Asp + Glu) 58

MurF

A0A0R4J6Z4

466

50.8

5.87

− 0.130

33.75

93.45

3

25565

>10

Cyto

(Arg + Lys) 37

(Asp + Glu) 49

MraY

B0V8P2

372

40.9

9.54

0.781

25.10

126.32

1

70360

>10

CIM

(Arg + Lys) 26

(Asp + Glu) 17

MurG

B0V9F5

365

39.4

9.02

0.051

39.12

97.34

2

20190

>10

Cyto

(Arg + Lys) 34

(Asp + Glu) 28

  1. AA amino acid, Mw molecular weight, pI isoelectric point, GRAVY grand average of hydropathicity, II instability index, AI aliphatic index, D domain, EC extinction coefficients, L location, + R positively charged residues, − R negatively charged residues