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Table 1 Experimental design

From: Therapeutic potential of a novel combination of Curcumin with Sulfamethoxazole against carbon tetrachloride-induced acute liver injury in Swiss albino mice

GroupsDoseMethod of sectionDuration
Group I negative control0.5 ml olive oil/kg b.w.i.p3 times a week for 5 weeks
Group II DMSO control(0.2%) DMSOi.p3 times a week for 4 weeks
Group III CCl4 control1 ml (50% in olive oil)/kg b.w.i.p3 times a week for 5 weeks
Group IV CUR groupCCl4 as group III followed by CUR 100 mg/kg b.w. in olive oil [45, 46]CCl4 i.p
CUR orally through a gastric tube
CCl4 3 times a week for 5 weeks then
4 times a week for 4 weeks
Group V CUR control100 mg/kg b.w. in olive oil [45, 46]orally through a gastric tube4 times a week for 4 weeks
Group VI SMX GroupCCl4 as group III followed by 15 mg SMX/kg b.w. in DMSO [47]i.pCCl4 3 times a week for 5 weeks then
4 times a week for 4 weeks
Group VII SMX control15 mg SMX/kg b.w. in DMS O[47]i.p4 times a week for 4 weeks
Group VIII Combination (CUR + SMX) groupCCl4 as group III followed by CUR as group V and SMX as group VIICCl4 and SMX i.p
CUR orally through a gastric tube.
CCl4 3 times a week for 5 weeks then
4 times a week for 4 weeks
Group IX Combination (CUR. + SMX.) controlCUR as group V and SMX as group VIICUR orally through a gastric tube. SMX i.p4 times a week for 4 weeks
  1. CCl4 carbon tetrachloride, CUR curcumin, SMX sulfamethoxazole, i.p intraperitoneally